Opportunity Information: Apply for HT9425 23 LCRP CDA
The FY23 Department of Defense Lung Cancer Research Program (LCRP) Career Development Award is designed to help early-career investigators build independent research careers in lung cancer by pairing them with strong mentorship and providing support for a discovery-focused research project. The program targets research- and physician-scientists who are still near the beginning of their independent faculty trajectory and who want to establish themselves as leaders in lung cancer research. A key restriction is that applications focused only on mesothelioma are not allowed, so proposed projects must address lung cancer more broadly (or other LCRP-relevant lung malignancies) rather than being solely mesothelioma-centered.
This award specifically supports principal investigators (PIs) who are within five years of their first faculty appointment or an equivalent independent position. In other words, it is geared toward investigators who have already transitioned out of trainee roles and into independence, but who still need resources, mentorship, and a track record of results to become fully established. The expectation is that the PI demonstrates a clear commitment to lung cancer research as a long-term career focus, not just a one-off project.
Mentorship is a central feature rather than a formality. Applicants must identify one or more mentors who are experienced lung cancer researchers, with a strong history of funding and publications that shows they are well positioned to guide an early-career investigator. Beyond credentials, the mentor team must also convey a real commitment to the PI's growth, meaning active involvement in training, advising, and helping the PI develop the scientific and professional skills needed to become an independent, competitive researcher in this field.
A structured Career Development Plan is required and should be built collaboratively with the mentor(s). This plan needs to spell out how the PI will gain the skills, technical expertise, and research experience necessary to operate at the forefront of lung cancer research. Because the award is explicitly career-development oriented, the PI must commit at least 25 percent effort to the supported lung cancer research during the project period. That time commitment signals that the award is meant to meaningfully shape the PI's trajectory, not sit on the margins of other responsibilities.
On the science side, the award prioritizes impactful, discovery-driven projects that could move the field forward in meaningful ways. Preliminary data are not required, which lowers a common barrier for early-career investigators. At the same time, the application still needs to be scientifically convincing: the proposed work must be grounded in logical reasoning, a clear hypothesis or conceptual framework, and a sound rationale that explains why the approach is likely to produce important insights or advances.
A consistent expectation across the DOD medical research portfolio is relevance to the Military Health System (MHS). For this opportunity, applicants must clearly explain how the proposed lung cancer research matters to Service Members, Veterans, and their families. That relevance could be tied to risk factors, exposures, screening and early detection needs, treatment challenges, survivorship issues, or other concerns that disproportionately affect or are especially important to military-connected populations. The proposal should not treat this as a generic statement; it should make a specific, credible case for how the work could benefit these communities.
Administratively, this funding opportunity is offered by the Department of Defense (Department of the Army, USAMRAA) under CFDA 12.420 and can be made as a grant or cooperative agreement. Eligibility is listed as unrestricted, meaning a wide range of applicant organizations may apply as long as they meet any requirements described in the full announcement. The opportunity number is HT9425-23-LCRP-CDA, with an anticipated three awards. The listed award ceiling is shown as 0 in the provided source data, which typically indicates that applicants need to consult the full funding announcement for budget limits or that the ceiling is not captured in that particular summary field. An additional program requirement is that the PI must attend a one-day DOD in-progress review meeting before the end of the second year of the award, which reflects the program's emphasis on oversight, progress tracking, and engagement with the broader DOD research community.Apply for HT9425 23 LCRP CDA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Lung Cancer, Career Development Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on Feb 16, 2023.
- Applicants must submit their applications by May 23, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: FY23 DOD Lung Cancer Research Program (LCRP) Career Development Award (CDA)
What is the FY23 DOD LCRP Career Development Award intended to support?
The Career Development Award is designed to help early-career investigators build independent research careers in lung cancer. It does this by pairing the principal investigator (PI) with strong mentorship and providing support for a discovery-focused lung cancer research project.
Who is this award meant for?
This award targets early-career research scientists and physician-scientists who are near the beginning of their independent faculty trajectory and want to establish themselves as leaders in lung cancer research.
How does the program define "early-career" eligibility for the PI?
The PI must be within five years of their first faculty appointment or an equivalent independent position. The intent is to support investigators who have already transitioned into independence (not trainee roles), but who still need mentorship, resources, and results to become fully established.
Is mentorship optional or required?
Mentorship is a core requirement of this award. Applicants must identify one or more mentors, and the application is expected to show that the mentor team will be actively involved in the PI's development rather than serving as a nominal advisor.
What qualifications are expected for the mentor or mentor team?
Mentors are expected to be experienced lung cancer researchers with a strong history of funding and publications. In addition to credentials, they must demonstrate a meaningful commitment to supporting the PI's scientific and professional growth.
Do applicants need to submit a Career Development Plan?
Yes. A structured Career Development Plan is required and should be developed collaboratively with the mentor(s). The plan should outline how the PI will gain skills, technical expertise, and research experience needed to operate at the forefront of lung cancer research.
What level of effort must the PI commit to the project?
The PI must commit at least 25 percent effort to the supported lung cancer research during the project period. This requirement reflects that the award is meant to play a substantial role in shaping the PI's career trajectory.
What kind of research projects does the award prioritize?
The award prioritizes impactful, discovery-driven lung cancer research projects that could move the field forward in meaningful ways. Even though preliminary data are not required, the project must still be scientifically convincing and logically framed.
Are preliminary data required to apply?
No. Preliminary data are not required, which can reduce a common barrier for early-career investigators.
If preliminary data are not required, what does the application still need to show scientifically?
The proposed work still needs a clear hypothesis or conceptual framework, a sound rationale, and logical reasoning that supports why the approach is likely to produce important insights or advances in lung cancer research.
Are mesothelioma-only applications allowed?
No. A key restriction is that applications focused only on mesothelioma are not allowed. Proposed projects must address lung cancer more broadly or other LCRP-relevant lung malignancies, rather than being solely mesothelioma-centered.
Can a project include mesothelioma at all?
The information provided states that projects cannot be focused only on mesothelioma. It also indicates that projects must address lung cancer more broadly (or other LCRP-relevant lung malignancies) rather than being solely mesothelioma-centered.
What does "relevance to the Military Health System (MHS)" mean for this opportunity?
Applicants must clearly explain how the proposed lung cancer research matters to Service Members, Veterans, and their families. The proposal should make a specific, credible case for how the work could benefit military-connected communities, rather than relying on generic statements.
What are examples of Military Health System relevance areas mentioned in the opportunity description?
The description notes that relevance could be tied to risk factors, exposures, screening and early detection needs, treatment challenges, survivorship issues, or other concerns that disproportionately affect or are especially important to military-connected populations.
Is the award meant to support a one-time lung cancer project?
No. The expectation is that the PI demonstrates a clear commitment to lung cancer research as a long-term career focus, not just a one-off project.
Who is the sponsoring agency and what program identifier is associated with this funding?
This opportunity is offered by the Department of Defense (Department of the Army, USAMRAA) under CFDA 12.420.
What is the opportunity number for this funding announcement?
The opportunity number is HT9425-23-LCRP-CDA.
How many awards are anticipated?
The opportunity lists an anticipated three awards.
Is the funding mechanism a grant or a cooperative agreement?
The opportunity indicates that funding can be made as either a grant or a cooperative agreement.
What does "eligibility is unrestricted" mean here?
The description states that eligibility is unrestricted, meaning a wide range of applicant organizations may apply as long as they meet any requirements described in the full announcement.
Is there a stated maximum award amount (ceiling)?
The listed award ceiling is shown as 0 in the provided source data. This typically means applicants should consult the full funding announcement for budget limits, or that the ceiling is not captured in the summary field provided.
Are there any special meeting or reporting requirements for awardees?
Yes. The PI must attend a one-day DOD in-progress review meeting before the end of the second year of the award. This reflects an emphasis on oversight, progress tracking, and engagement with the broader DOD research community.
When must the in-progress review meeting be attended?
The PI is required to attend the one-day DOD in-progress review meeting before the end of the second year of the award.
Why does the program emphasize mentorship and a career development plan?
The award is explicitly career-development oriented. Mentorship and the Career Development Plan are intended to help the PI build the skills, research experience, and professional development needed to become an independent, competitive lung cancer researcher.
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