Opportunity Information: Apply for PAR 18 388
Education and Health: New Frontiers (R03) - Clinical Trial Optional (PAR 18 388) is a National Institutes of Health (NIH) discretionary grant opportunity designed to fund small, focused research projects that dig into how education shapes health. The central aim is not just to restate the well-known link between higher educational attainment and better health outcomes, but to unpack the pathways that produce that link. In practical terms, the program is looking for research that can identify which specific aspects of education (for example, quality, timing, content, credentials, learning environments, or institutional features) appear to be driving health effects, and which mediating factors (such as income, occupation, health behaviors, stress, access to care, social networks, cognitive skills, or neighborhood context) help explain how education ultimately translates into differences in health.
Because the announcement emphasizes clarifying causal relationships, it is geared toward studies that can carefully test mechanisms rather than simply documenting correlations. The phrase "New Frontiers" signals an interest in sharper conceptual models, improved measurement of educational experiences, and stronger designs that can isolate the contributions of education itself from related influences like family background or local economic conditions. The "clinical trial optional" designation means an applicant can propose work that includes a clinical trial component, but it is not required; many competitive projects under this kind of call may be observational, quasi-experimental, secondary data analysis, methodological, or pilot in nature, so long as they directly advance understanding of education-to-health mechanisms.
This opportunity uses the NIH R03 mechanism, which generally supports short-term, limited-scope projects, often including pilot or feasibility studies, secondary analyses, or early-stage investigations that can generate preliminary findings for larger future awards. The listed award ceiling is $50,000, reflecting the small-grant nature of the mechanism and encouraging tightly defined research questions and efficient study plans.
Eligibility is broad and includes a wide mix of public, private, nonprofit, and for-profit entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public housing authorities/Indian housing authorities; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The announcement also highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, U.S. territories or possessions, tribal governments that are not federally recognized, and non-U.S. (foreign) organizations.
Key administrative details from the source information include: the agency is the National Institutes of Health; the funding instrument type is a grant; the activity category spans education, health, income security, and social services; and the opportunity is associated with CFDA numbers 93.279, 93.399, 93.865, and 93.866. The opportunity record shows a creation date of 2017-11-22 and an original closing date of 2019-01-07, indicating the timeline for that particular posting.Apply for PAR 18 388
- The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Education and Health: New Frontiers (R03) - Clinical Trial Optional" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279, 93.399, 93.865, 93.866.
- This funding opportunity was created on 2017-11-22.
- Applicants must submit their applications by 2019-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| Education and Health: New Frontiers (R21)- Clinical Trial Optional Apply for PAR 18 362 Funding Number: PAR 18 362 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21 Clinical Trial Optional) Apply for PAR 18 242 Funding Number: PAR 18 242 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $125,000 |
| Surgical Disparities Research (R01 Clinical Trial Optional) Apply for PAR 18 288 Funding Number: PAR 18 288 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Developing the Therapeutic Potential of the Endocannabinoid System for Pain Treatment (R01, Clinical Trial Optional) Apply for PA 18 465 Funding Number: PA 18 465 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Development, Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42 Clinical Trial Not Allowed) Apply for PAR 18 515 Funding Number: PAR 18 515 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Biology and Biophysics of Neural Stimulation (R01 - Clinical Trials Optional) Apply for RFA NS 18 018 Funding Number: RFA NS 18 018 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Targeted BRAIN Circuits Planning Projects TargetedBCPP (R34 - Clinical Trials Not Allowed) Apply for RFA NS 18 014 Funding Number: RFA NS 18 014 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $225,000 |
| BRAIN Initiative: Development, Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (SBIR)(R43/R44 Clinical Trial Not Allowed) Apply for PAR 18 501 Funding Number: PAR 18 501 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44) - Clinical Trial Optional Apply for PAR 18 541 Funding Number: PAR 18 541 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 - Clinical Trial Required) Apply for RFA NS 18 021 Funding Number: RFA NS 18 021 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required) Apply for RFA NS 18 022 Funding Number: RFA NS 18 022 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Clinical Studies to Advance Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (UH3 - Clinical Trial Required) Apply for RFA NS 18 023 Funding Number: RFA NS 18 023 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3) - Clinical Trial Optional Apply for PAR 18 546 Funding Number: PAR 18 546 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) Apply for PA 18 573 Funding Number: PA 18 573 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 18 576 Funding Number: PA 18 576 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: New Concepts and Early - Stage Research for Large - Scale Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed) Apply for RFA EY 18 001 Funding Number: RFA EY 18 001 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| BRAIN Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System (R01 Clinical Trials Not Allowed) Apply for RFA NS 18 020 Funding Number: RFA NS 18 020 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01-Clinical Trials Not Allowed) Apply for RFA NS 18 019 Funding Number: RFA NS 18 019 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Reducing Stigma to Improve HIV/AIDS Prevention, Treatment and Care in Low and Middle- Income Countries (R21 Clinical Trial Optional) Apply for PAR 18 732 Funding Number: PAR 18 732 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $125,000 |
| Addressing the Challenges of the Opioid Epidemic in Minority Health and Health Disparities Research in the U.S. (R21 Clinical Trial Optional) Apply for PAR 18 745 Funding Number: PAR 18 745 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
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