Opportunity Information: Apply for RFA PS 21 002
The funding opportunity titled "Implementation Research Consortium to Accelerate Impact of Health Department-Delivered HIV Prevention Activities" (RFA PS 21 002) is a discretionary federal grant offered by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC). It is structured as a cooperative agreement, which generally means awardees should expect an active partnership with CDC staff during the project period, with substantial federal involvement in coordination, technical input, and oversight compared with a typical grant.
The central purpose of the announcement is to strengthen how proven HIV prevention interventions are carried out in real-world public health settings, particularly those delivered by health departments. Rather than funding the discovery of entirely new interventions, this opportunity emphasizes implementation research: studying and improving the practical steps that determine whether evidence-based prevention strategies are adopted, delivered with quality, scaled effectively, and sustained over time. A key feature is the creation of a collaborative research infrastructure, essentially a consortium that links experts and organizations so they can coordinate methods, share learning, and accelerate progress. The work is explicitly aligned with the federal Ending the HIV Epidemic (EHE) initiative, meaning projects are expected to contribute to measurable improvements in prevention impact and system performance in ways that support EHE goals.
CDC anticipated supporting multiple projects under this announcement, with an expected four (4) awards for Core Projects and two (2) awards for Collaborative Projects. While the source text does not define these categories in detail, the labeling signals two tiers of work: Core Projects likely form the backbone of the consortium's research and operations, while Collaborative Projects likely focus on cross-site or cross-team efforts that knit the consortium together and enable shared analyses, common measures, or coordinated pilots.
The opportunity is open to a wide range of applicants across government, academia, and the private and nonprofit sectors. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education in those categories); for-profit organizations other than small businesses; and small businesses. This broad eligibility reflects the reality that HIV prevention implementation often involves partnerships among health departments, universities, community-based organizations, and sometimes private-sector service or data partners.
From an administrative perspective, the notice was created on November 9, 2020, and the original application deadline was January 28, 2021, with electronic submissions due no later than 5:00 p.m. Eastern Time on the due date. The maximum award amount listed is $1,150,000 (award ceiling). The activity category is Health, and the funding is associated with CFDA numbers 93.084, 93.941, and 93.943, which correspond to CDC assistance listings that commonly support HIV-related prevention and public health work.
In practical terms, applicants responding to this NOFO would be positioning research teams to help health departments increase the real-world impact of HIV prevention activities by addressing implementation barriers, improving delivery strategies, and generating actionable evidence that can be used quickly. The emphasis on a consortium signals that CDC was looking for coordinated, shareable learning rather than isolated studies, with the overall intent of accelerating improvements that advance the Ending the HIV Epidemic national plan.Apply for RFA PS 21 002
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Implementation Research Consortium to Accelerate Impact of Health Department-Delivered HIV Prevention Activities" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084, 93.941, 93.943.
- This funding opportunity was created on Nov 09, 2020.
- Applicants must submit their applications by Jan 28, 2021 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,150,000.00 in funding.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses.
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| Client-Oriented Response for HIV Epidemic Control (CORE) Activity Apply for 72061220RFA00015 Funding Number: 72061220RFA00015 Agency: Agency for International Development, Malawi USAID-Lilongwe Category: Health Funding Amount: $80,000,000 |
| Epidemiologic Cohort Study of Interstitial Cystitis Apply for RFA DP 21 002 Funding Number: RFA DP 21 002 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $900,000 |
| Conducting Public Health Research in Thailand: Technical collaboration with the Ministry of Public Health (MOPH) in the Kingdom of Thailand Apply for RFA GH 21 001 Funding Number: RFA GH 21 001 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $7,000,000 |
| Conducting Public Health Research in Ethiopia Apply for RFA GH 21 005 Funding Number: RFA GH 21 005 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $250,000 |
| Strengthening Public Health Research and Implementation Science (Operations Research) to Control and Eliminate Infectious Diseases Globally Apply for RFA GH 21 006 Funding Number: RFA GH 21 006 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $2,000,000 |
| Building Capacity to Improve Collecting and Reporting Viral Suppression Data to the Medicaid Adult Core Set Apply for HRSA 21 083 Funding Number: HRSA 21 083 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $4,000,000 |
| Leadership Education in Neurodevelopmental and Other Related Disabilities (LEND) Apply for HRSA 21 041 Funding Number: HRSA 21 041 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Promoting the Importance of Infant and Childhood Vaccination Among Pregnant Women by Prenatal Care Providers Apply for RFA IP 21 001 Funding Number: RFA IP 21 001 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $500,000 |
| US Enhanced Surveillance Network to Assess Burden, Natural History, and Effectiveness of Vaccines to Prevent Enteric and Respiratory Viruses in Children Apply for RFA IP 21 002 Funding Number: RFA IP 21 002 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $1,950,000 |
| Advanced Nursing Education - Sexual Assault Nurse Examiners (ANE-SANE) Program Apply for HRSA 21 016 Funding Number: HRSA 21 016 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $500,000 |
| National Maternal and Child Health Consortium for Oral Health Systems Integration and Improvement Apply for HRSA 21 037 Funding Number: HRSA 21 037 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $1,325,000 |
| Integrated Health Services in Burkina Faso Apply for 72068521RFA00001 Funding Number: 72068521RFA00001 Agency: Agency for International Development, Senegal USAID-Dakar Category: Health Funding Amount: $39,000,000 |
| National Urban Indian Behavioral Health Awareness Apply for HHS 2020 IHS UIHP3 0001 Funding Number: HHS 2020 IHS UIHP3 0001 Agency: Department of Health and Human Services, Indian Health Service Category: Health Funding Amount: $75,000 |
| Nursing Workforce Diversity (NWD) Program Apply for HRSA 21 020 Funding Number: HRSA 21 020 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Rapid Response Rural Data Analysis and Issue Specific Rural Research Studies Apply for HRSA 21 029 Funding Number: HRSA 21 029 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $500,000 |
| Zimbabwe Assistance Program in Malaria II (ZAPIM II) Apply for 72061321RFA00001 Funding Number: 72061321RFA00001 Agency: Agency for International Development, Zimbabwe USAID-Harare Category: Health Funding Amount: $19,700,000 |
| State Offices of Rural Health Program (SORH) Apply for HRSA 21 026 Funding Number: HRSA 21 026 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $230,000 |
| Small Vessel VCID Biomarkers Validation Consortium Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA NS 21 004 Funding Number: RFA NS 21 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Small Vessel VCID Biomarker Validation Consortium Sites (U01)(Clinical Trials Not Allowed) Apply for RFA NS 21 005 Funding Number: RFA NS 21 005 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $800,000 |
| Ryan White HIV/AIDS Program Part C Capacity Development Program Apply for HRSA 21 058 Funding Number: HRSA 21 058 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
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