Opportunity Information: Apply for PA 19 029
The Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (PA 19-029) is a Department of Health and Human Services, National Institutes of Health funding opportunity designed to strengthen the national innovation ecosystem by helping biomedical discoveries move out of the lab and into real-world use. The central purpose is not to fund new research experiments, but to educate and coach teams on the practical work of commercialization: understanding customer needs, mapping markets, testing assumptions, and shaping a viable path for a technology, product, or service that can benefit society. In short, it is a translation and commercialization training-and-mentoring program built around NIH- and CDC-funded small business innovations.
This FOA is offered as an administrative supplement mechanism for small businesses that already hold active SBIR or STTR Phase I awards from participating NIH and CDC Institutes and Centers. Eligibility is therefore narrow and targeted: the applicant must be a small business with an ongoing Phase I SBIR/STTR project that aligns with a participating Institute or Center. Rather than operating like a typical standalone grant with a large project budget, the supplement is meant to support participation in the I-Corps curriculum and associated customer discovery and commercialization development activities. The FOA is explicitly labeled “Clinical Trial Not Allowed,” meaning applicants should not propose clinical trials under this supplement; the emphasis remains on commercialization readiness and market validation for technologies already under development through the parent Phase I award.
A defining feature of the program is its team-based structure. Applicants are expected to form a three-member project team that can engage fully in instruction and mentoring. While the FOA summary does not list role titles in the excerpt provided, the intent is to bring together the core perspectives needed to move a technology toward the marketplace: a scientific or technical lead who understands the innovation deeply, an entrepreneurial lead who can drive customer discovery and business-model learning, and a mentor-type contributor who brings commercialization experience and external perspective. Through structured training and intensive guidance, teams are pushed to get out of the building, talk to stakeholders, and gather evidence about who the customers are, what problems are worth solving, and what adoption, reimbursement, regulatory, and competitive realities will shape the route to market.
The expected outcomes focus on sharper, more defensible commercialization plans and better strategic decision-making. By the end of participation, teams are expected to have validated or corrected key assumptions about market need and product-market fit, and to have made “well-informed pivots” when the evidence suggests a different application, target user, channel, or business model is more realistic. The program is designed to accelerate translation by reducing guesswork early, so Phase I projects can transition into stronger Phase II plans, follow-on investment conversations, partnerships, licensing strategies, or other commercialization pathways with clearer rationale and reduced risk.
Administratively, this is a discretionary grant opportunity categorized under education and health-related activity areas, with multiple CFDA numbers listed because many NIH/CDC components can participate across diverse biomedical domains. The opportunity was created October 17, 2018, with an original closing date of January 28, 2019, and it anticipated about 24 awards. The listing shows an award ceiling of 0, which is commonly seen in postings where the amount is not expressed as a single fixed cap in the summary table and instead depends on administrative supplement policies and Institute/Center participation.
A practical point emphasized in the announcement is pre-application communication. Prospective applicants are strongly encouraged to contact NIH or CDC scientific/research staff before applying to confirm fit, clarify expectations for the supplement request, and understand how the I-Corps program will be implemented by the relevant Institute or Center. This step matters because the award depends on the existing parent SBIR/STTR Phase I grant, Institute/Center participation, and alignment with program goals centered on commercialization learning rather than additional R&D.Apply for PA 19 029
- The Department of Health and Human Services, National Institutes of Health in the education, environment, food and nutrition, health sector is offering a public funding opportunity titled "Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084, 93.113, 93.121, 93.172, 93.173, 93.213, 93.242, 93.262, 93.273, 93.279, 93.350, 93.351, 93.393, 93.394, 93.395, 93.396, 93.397, 93.398, 93.399, 93.846, 93.847, 93.853, 93.855, 93.866, 93.867.
- This funding opportunity was created on Oct 17, 2018.
- Applicants must submit their applications by Jan 28, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 24 candidate(s).
- Eligible applicants include: Small businesses.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 19 029) also looked into and applied for these:
| Funding Opportunity |
|---|
| Specialized Centers of Research Excellence (SCORE) on Sex Differences (U54 Clinical Trial Optional) Apply for RFA OD 19 013 Funding Number: RFA OD 19 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: $1,000,000 |
| Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42) Apply for PA 17 148 Funding Number: PA 17 148 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44) Apply for PA 17 147 Funding Number: PA 17 147 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Administrative Supplements for Research on Dietary Supplements (Admin Supp) Apply for PA 17 307 Funding Number: PA 17 307 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: $100,000 |
| Administrative supplements for validation studies of analytical methods for dietary supplements and natural products (Admin. Suppl.) Apply for PA 17 447 Funding Number: PA 17 447 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Administrative Supplements for Validation Studies of Analytical Methods for Dietary Supplement Constituents (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 818 Funding Number: PA 18 818 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Methods to Improve Reproducibility of Human iPSC Derivation, Growth and Differentiation (SBIR) (R44 Clinical Trial Not Allowed) Apply for RFA GM 19 001 Funding Number: RFA GM 19 001 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: $375,000 |
| SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, R44) Clinical Trial Not Allowed Apply for PAR 19 334 Funding Number: PAR 19 334 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| USAID Cambodia Integrated Early Childhood Development Activity Apply for 72044220RFA00001 Funding Number: 72044220RFA00001 Agency: Cambodia USAID-Phnom Penh Category: Education, Environment, Food and Nutrition, Health Funding Amount: $15,000,000 |
| Community Interventions to Address the Consequences of the COVID-19 Pandemic among Health Disparity and Vulnerable Populations (R01- Clinical Trial Optional) Apply for PAR 20 237 Funding Number: PAR 20 237 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: $500,000 |
| SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, Clinical Trial Not Allowed) Apply for PAR 20 128 Funding Number: PAR 20 128 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Validation Studies of Analytical Methods for Dietary Supplement Constituents (Admin Supp - Clinical Trial Not Allowed) Apply for PA 20 252 Funding Number: PA 20 252 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) Apply for PA 20 272 Funding Number: PA 20 272 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) Apply for PA 21 151 Funding Number: PA 21 151 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Identification and Characterization of Bioactive Microbial Metabolites for Advancing Research on Microbe-Diet-Host Interactions (R01 Clinical Trial Not Allowed) Apply for PAR 21 253 Funding Number: PAR 21 253 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Required) Apply for PAR 21 272 Funding Number: PAR 21 272 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed) Apply for PAR 21 271 Funding Number: PAR 21 271 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional) Apply for PAR 22 078 Funding Number: PAR 22 078 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Specialized Centers of Research Excellence (SCORE) on Sex Differences (U54 Clinical Trial Optional) Apply for RFA OD 22 014 Funding Number: RFA OD 22 014 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
| Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional) Apply for PAR 23 156 Funding Number: PAR 23 156 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health Funding Amount: Case Dependent |
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